A US patient with leukemia has become the first woman and the third person in the world so far to be cured of HIV after receiving a stem cell transplant from a donor who was naturally resistant to the virus that causes AIDS, researchers reported in this paper. Tuesday (15th).
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The 64-year-old multiracial patient’s case presented at the Denver Conference on Retroviruses and Opportunisitic Infections is also the first involving cord blood, a novel approach that could make treatment available to more people.
Since receiving cord blood to treat her acute myeloid leukemia (AML) – a cancer that starts in the blood-forming cells of the bone marrow – the woman has been in remission and virus-free for 14 months, and has not had any treatment. potent for HIV, such as so-called antiretroviral therapies (ART).
The two cases before this one occurred in men – one white and one Latino – who received adult stem cells, most often used in bone marrow transplants.
“This is now the third reported cure in this setting, and the first in a woman living with HIV,” Sharon Lewin, president-elect of the International AIDS Society (IAS), said in a statement.
Scientists believe that these individuals develop an HIV-resistant immune system. “Together, these three cases of post-stem cell transplant healing help unravel the various components of the transplant that were absolutely essential to the healing,” Lewin said.
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